Environmental Health Sciences Center

Christoph Vogel is a Professional Researcher at the Department of Environmental Toxicology and Center for Health and the Environment. His lab focuses on the function of receptors for xenobiotics and inflammatory signaling to understand molecular mechanisms of the development of chronic inflammatory diseases promoted by exposure to environmental toxicants and non-chemical stressors. Their mission is to better understand how both helpful and harmful molecules affect our bodies at a molecular level, providing insights into how environmental pollutants can lead to the development of chronic diseases.

Positions at UC Davis

• Professional Researcher, Department of Environmental Toxicology and Center for Health and the Environment
• Principal Investigator, Vogel Lab

Area of Expertise

• Molecular and Environmental Toxicology

Major Research Papers

Holme JA, Vondráček J, Machala M, Lagadic-Gossmann D, Vogel CFA, Le Ferrec E, Sparfel L, Øvrevik J. Lung cancer associated with combustion particles and fine particulate matter (PM2.5) - The roles of polycyclic aromatic hydrocarbons (PAHs) and the aryl hydrocarbon receptor (AhR). Biochem Pharmacol. 2023 Oct;216:115801. doi: 10.1016/j.bcp.2023.115801. Epub 2023 Sep 9. PMID: 37696458; PMCID: PMC10543654.

Kado SY, Bein K, Castaneda AR, Pouraryan AA, Garrity N, Ishihara Y, Rossi A, Haarmann-Stemmann T, Sweeney CA, Vogel CFA. Regulation of IDO2 by the Aryl Hydrocarbon Receptor (AhR) in Breast Cancer. Cells. 2023 May 20;12(10):1433. doi: 10.3390/cells12101433. PMID: 37408267; PMCID: PMC10216785.

Tanaka M, Okuda T, Itoh K, Ishihara N, Oguro A, Fujii-Kuriyama Y, Nabetani Y, Yamamoto M, Vogel CFA, Ishihara Y. Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation. Part Fibre Toxicol. 2023 Feb 16;20(1):6. doi: 10.1186/s12989-023-00517-x. PMID: 36797786; PMCID: PMC9933276.

Sweeney C, Lazennec G, Vogel CFA. Environmental exposure and the role of AhR in the tumor microenvironment of breast cancer. Front Pharmacol. 2022 Dec 15;13:1095289. doi: 10.3389/fphar.2022.1095289. PMID: 36588678; PMCID: PMC9797527.

Sondermann NC, Faßbender S, Hartung F, Hätälä AM, Rolfes KM, Vogel CFA, Haarmann-Stemmann T. Functions of the aryl hydrocarbon receptor (AHR) beyond the canonical AHR/ARNT signaling pathway. Biochem Pharmacol. 2023 Feb;208:115371. doi: 10.1016/j.bcp.2022.115371. Epub 2022 Dec 15. PMID: 36528068; PMCID: PMC9884176.