Michele LaMerrill

Position Title
Member, Environmental Health Sciences Center

Bio

Dr. Michele LaMerril is an Associate Professor of Environmental Toxicology who studies the developmental basis of environmental causes of endocrine disease including obesity, diabetes, and breast cancer.

The La Merrill laboratory conducts epidemiological studies to integrate human observations with mechanistic investigations. Their goal is to improve disease prevention through primary prevention of exposure and secondarily through lifestyle- and pharmaceutical- interventions.

Position at UC Davis

  • Assistant Professor, Environmental Toxicology

Areas of Expertise

  • Environmental Toxicology
  • Genetic and Developmental Pharmacology
  • Metabolic Fate
  • Pharmacokinetics

Major Research Papers

La Merrill MA. The environmental chemicals that change our minds and bodies. The Lancet Diabetes & Endocrinology, 2019, 8: 16, doi: 10.1016/S2213-8587(19)30177-9.

La Merrill MA*, Vandenberg LN, Smith MT, Goodson W, Browne P, Patisaul HB, Guyton KZ, Kortenkamp A, Cogliano VJ, Woodruff TJ, Rieswijk L, Sone H, Korach KS, Gore AC, Zeise L, Zoeller TR. Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. Nature Reviews Endocrinology, 2019, doi:10.1038/s41574-019-0273-8.

Castriota F, Rieswijk L, Dahlberg S, La Merrill MA, Steinmaus C, Smith MT, Wang JC. A state-of-the-science review of arsenic’s effects on glucose homeostasis in experimental models. Environmental Health Perspective, 2020, 128,16001,doi:10.1289/EHP4517, PMID31898917.

Smith M, Guyton KZ, Kleinstreuer N, Borrel A, Cardenas A, Chiu W, Felsher DW, Gibbons C, Goodson W, Houck K, La Merrill MA, Lebrec H, Lowe L, McHale C, Minocherhomji S, Rieswijk L, Sandy M, Hideko S, Wang A, Zhang L, Zeise L, Fielden M. The key characteristics of carcinogens: relationship to the hallmarks of cancer, relevant biomarkers, and assays to measure them. Cancer Epidemiology and Prevention Biomarkers, 2020, doi:10.1158/1055-9965.EPI-19-1346, PMID32152214.

Rider CV, McHale CM, Webster TF, Lowe L, Goodson WH, La Merrill MA, Rice G, Zeise L, Zhang L, Smith MT. Using the key characteristics of carcinogens to develop research on chemical mixtures and cancer. Environmental Health Perspectives, 2021, doi:10.1289/EHP8525, PMID33784186

Education and Degree(s)
  • BA, Biology, Reed College, 2002
  • PhD, Toxicology, University of North Carolina (UNC) at Chapel Hill, 2008
  • MPH, Mount Sinai School of Medicine (MSSM), 2010
  • Postdoctoral Fellow, Mount Sinai School of Medicine (MSSM), 2012
Honors and Awards
  • Environmental Mutagen Society (EMS) Travel Award, Annual Meeting of the EMS (2008)
  • Tuition Scholarship, Colony Management: Principles and Practices, Jackson Laboratories (2008)
  • Endocrine Trainee Day Travel Award, Annual Meeting of the Endocrine Society (2009)
  • Best Manuscript in the Occupational and Public Health Specialty Section, Society of Toxicology (SOT) (2009)
  • PPTOXII Student Travel Award, PPTOXII: Role of Environmental Stressors in the Developmental Origins of Disease Workshop (2009)
  • Outstanding Postdoctoral Fellow Award, Women in Toxicology, Annual Meeting of the SOT (2010)
  • AstraZeneca Travel Award, Cellular & Molecular Mechanisms of Toxicity Gordon Research Conference (GRC) (2011)
  • PPTOXIII Travel Award, PPTOXIII: Environmental Stressors in the Developmental Origins of Disease: Evidence and Mechanisms Workshop (2012)